The cardiac pacemaker-specific channel Hcn4 is a direct transcriptional target of MEF2
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چکیده
منابع مشابه
The cardiac pacemaker-specific channel Hcn4 is a direct transcriptional target of MEF2.
AIMS Hcn4, which encodes the hyperpolarization-activated, cyclic nucleotide-sensitive channel (I(h)), is a well-established marker of the cardiac sino-atrial node. We aimed to identify cis-elements in the genomic locus of the Hcn4 gene that regulate the transcription of Hcn4. METHODS AND RESULTS We screened evolutionarily conserved non-coding sequences (CNSs) that are often involved in the re...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2009
ISSN: 1755-3245,0008-6363
DOI: 10.1093/cvr/cvp171